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Transcription Element Search Software (TESS)
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Very helpful software for locating and displaying transcription factor binding sites within DNA sequences - from the Univ. of Penn.
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BioMolecular Engineering Research Center
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Tools and methods for computational biology. Working on secondary protein structure prediction, providing reliable profiles, and developing new ways to study molecular biology through bioinformatics.
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Entrez Browser
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Retrieves molecular biology data and bibliographic citations from the NCBI's integrated databases.
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Geneva Bioinformatics (GeneBio) S.A.
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GeneBio provides proteomics software tools and databases including SWISS-PROT, PROSITE, SWISS-2DPAGE and Melanie. We also offer a secure version of ExPASy molecular biology web server.
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Transterm - a database of mRNA regions and motifs
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Transterm - an interactive database of mRNA regions and motifs from all species and genomes. Users can browse the pre-computed data tables, search the sequence databases or search their own sequences.
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INCBI Irish National Centre for BioInformatics
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Hosts Irish embnet node, Gives links to Database browsing and interrogation at SRS, European (EBI) servers, Blast server for parasite genomes (EBI), US (NCBI) servers, Protein structure prediction, PredictProtein Server in Heidelberg, Gene identification, splice sites, exons, introns and a list of gene structure prediction programs
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Searching GenBank
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Text and similarity searching, provided by the National Center for Biotechnology Information (NCBI).
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Sequence Analysis (Bielefeld University Bioinformatics Server)
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Collection of sequence analysis tools.
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NIH BioInformatics and Molecular Analysis Section
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Numerous computational tools and resources to unite advances in biology with those in computers, informatics, and networking for the genomic and genetic analysis fields of BioInformatics; division of the Computational Bioscience and Engineering Lab at the Center for Information Technology.
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PIR-International Protein Sequence Database
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produces a comprehensive, non-redundant, and expertly annotated protein sequence database. PIR features integrated annotation search to support functional/structural genomics and proteomic research.
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Genepop on the Web
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Online version of the program for populational genetics.
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SA National Bioinformatics Institute
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SANBI aims to bring genome information, computational biology, and analytical tools to the South African research community. Hosts SA National EMBNet Node, provides links to Sequence Retrieval System (SRS), GeneKraal, and TB Genomes Analysis Server. Research in Sequence Tag Alignment and Consensus Knowledgebase (STACK). Databases include BLAST search in Mycobacterium genome.
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Virtual Genome Center
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Online computational resources for PCR primer selection, similarity searching- from the Univ. of Minnesota.
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Center Structural Biology: Programs and Tools
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User guides and worked examples for software applications in structural and molecular biology - from Yale Univ.
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Biomolecular Interaction Network Database (BIND)
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BIND is a database designed to store full descriptions of interactions, molecular complexes and pathways.
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PEDANT
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Completely automatic and exhaustive analysis of protein sequence sets - from individual sequences to complete genomes
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CUBIC: Columbia University Bioinformatics Center
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Features PredictProtein service for sequence analysis and protein structure prediction, META for single-page interface to validated sequence analysis, PredictNLS for prediction and analysis of nuclear localization signals, EVA for evaluation of automatic protein structure prediction servers, and DSSPcont for continuous assignment of protein secondary structure.
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Molecular Interactions Database (MINT)
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MINT is a database designed to store functional interactions between biological molecules (proteins, RNA, DNA).
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Scansite
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Scansite searches for motifs within proteins that are likely to be phosphorylated by specific protein kinases or bind to domains such as SH2 domains, 14-3-3 domains or PDZ domains.
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Verbumculus Genetic Sequence Analyzer
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An interesting tool to discover and visualize over- or under-represented words in genetic sequences. Requires Java support in browser. Also available as a downloadable program.
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IBM Bioinformatics Group - Tools & Content
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Several genomics and proteomics tools, including multiple alignments, gene expression analysis, tandem repeat and motif discovery.
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ReadSeq
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Converts amino acid and nucleotide sequence data formats including FASTA, GenBank, Phylip and others.
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GenomeSURF
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Colorful visualization of Sequence Frequency. Includes Human and Mouse Genomic Sequences. Evaluate uniqueness of graphically.
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FIE (5' end Information Extraction)
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Gene sequence extraction of regions around the 5'-end (promoter) and/or the translation initiation site (TIS) of a gene.
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YMF - DNA Motif Finding Program
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Finds novel transcription factor binding sites by searching for over-represented (most significant motifs) motifs in DNA sequences.
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Web Services at Institute of Microbial Technology, Chandigarh, India
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Protein structure prediction (Protein Structural Classes, Secondary Structure Prediction), immunological methods (ProPred), genomics & proteomics (Genome Wise Sequence Similarity Search, Spectral Repeat Finder, 2D Gel Comparison, protein coding gene by Fast Fourier Transform), and biological databases.
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CAP Sequence Assembler
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DNA sequence assembly and contig formation.
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BIOBASE
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The focus of the GBF project "Molecular Bioinformatics of Gene Regulation" are regulatory genomic signals and regions that govern transcriptional control based on TRANSFAC - The Transcription Factor Database. It compiles data about gene regulatory DNA sequences and protein factors binding to and acting through them.
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ProteinLounge
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Bioinformatics portal which integrates protein information and many databases and research tools useful for researchers and students. Subscription based service.
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Kangaroo
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Search for motifs and paterns within amino acid and nucleotide databases
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General Repository for Interaction Datasets (GRID)
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The GRID is a database of genetic and physical interactions. It contains interaction data from many sources, including several genome/proteome-wide studies, the MIPS database, and BIND
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MedMiner
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An Internet biomedical data-mining tool for organizing search information gathered from textual or genetic databases - from the NIH National Cancer Inst.
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PlasMapper
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Online service to generate annotated plasmid maps up to 20 kbp. Outputs in PNG, JPG, SVG or SVGZ format.
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Bioverse
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Provides a framework for exploring the relationships among the molecular, genomic, proteomic, systems, and organismal worlds.
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Canadian Bioinformatics Help Desk
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We provide bioinformatics support, services, servers, and software to Canadian researchers.
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Mulan
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Performs single-coverage local multiple DNA sequence alignments of finished and draft-quality genome sequences. It also provides with an option to predict transcription factor binding sites evolutionarily conserved across multiple species.
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ProPred-I
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An online service for predicting MHC binding regions in antigens. It also offers the proteasomal and immunoproteasomal filters to improve the applicability of results.
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Ascidian Network
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An online database able to relate expression data with other data such as lineage, induction, cell fates, genomic information, blastomere position and morphology in the developing ascidian embryo.
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ParAlign
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Service using the ParAlign algorithm to compare genetic sequences. Apparently it is as fast as BLAST and as sensitive as Smith-Waterman.
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Systems Biology of Photosynthesis
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Open web platform for modeling and reverse engineering of photosynthetic dynamism.
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ERGO
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Online service integrating biological data from genomics, biochemistry, genetics and high-throughput expression profiling, to achieve a comprehensive pattern-based analysis of genes and genomes.
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Carnac
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A free software tool for analysing the hypothetical secondary structure of a family of homologous RNA.
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Gene Network Reconstruction
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Reconstruction of gene regulatory networks from time-series microarray expression data sets.
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PubCrawler
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An online service for periodically performing predefined searches at NCBI, reporting new results by email or on the web.
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Advanced Genetics Wizard
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Online program that calculates the distribution of offspring genotypes from dominant, codominant and recessive gene crosses, for up to 6 genes.
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iHOP
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Uses the network of genes and proteins as a natural way of accessing the millions of biomedical abstracts in PubMed.
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WebACT
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A database of sequence comparisons between all publicly available prokaryotic genome sequences, allowing the on-line visualisation of comparisons between up to five genomic sequences, using the Artemis Comparison Tool. User can perform their comparisons on their own data.
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TFM Explorer
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Scans sequences for potential Transcription Factor binding sites using Patser and TRANSFAC.
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Gene and Protein Synonyms DataBase
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Free service for retrieving all synonyms for a given gene or protein name.
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BioModels Database
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Resource for storing, searching and retrieving published mathematical models of biological interests. Models present in BioModels Database are annotated and linked to relevant data resources, such as publications, databases of compounds and pathways, controlled vocabularies, etc.
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InstaSeq
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Google-based search engine for DNA, RNA or Protein sequences.
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Gene Expression Data Analysis
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Normalization tests for differentially expressed genes, clustering, bootstrapping, leave-one-out validation, cross-fold validation.
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Center for Biological Sequence Analysis
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Offers more than 30 online services for DNA and protein bioinformatics analysis.
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PANDORA
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Protein ANnotation Diagram ORiented Analysis service that extracts biological information from user supplied sequences.
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JustBio: Online Tool Set
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A Suite of Online tools for analysis of DNA/RNA, Proteins, and Arrays.
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My Genomics Resource Centre
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A Malaysian Genomics toolset for high-throughput analysis of biological data. Must register to use.
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Bacterial Identification
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Service for the identification of bacteria and fungi sequences by sequence alignment.
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Information Génomique et Structurale (CNRS)
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Online services including T-Coffee, El-Nemo, Casper and FeeBack.
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Ligand-Gated Ion Channel Database
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LGICdb is a curated repository of genes coding for subunits of Ligand-Gated Ion Channels.
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Simulation programs for teaching population dynamics
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Offers a number of educational programs including LESLIE, LOGIST, CHAOS, CELLS, WITCOM, PRED and LEWONTIN.
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The Protein Information Resource
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In collaboration with the Munich Information Center for Protein Sequences (MIPS) and the Japanese International Protein Sequence Database (JIPID) maintains the PIR-International Protein Sequence Database --- a comprehensive, annotated, and non-redundant set of protein sequence databases in which entries are classified into family groups and alignments of each group are available.
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GenBank
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Text and similarity searching of the GenBank sequence database provided by the National Center for Biotechnology Information (NCBI).
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